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Release 14.1
Pathogen: Babesia bovis

Babesia bovis is a tick-borne apicomplexan parasite responsible for babesiosis, an economically important disease of cattle, and an emerging human zoonosis. Unlike relatives Plasmodium and Theleria, infection begins directly with erythrocyte invasion, but symptoms are similar to malaria, including anemia, sequestration, and neurological effects.

Name: Babesia bovis
Pathogen type: Protist
Description: Tick-borne protozoan parasite causing babesiosis in cattle
Lineage: Eukaryota » Alveolata » Apicomplexa » Aconoidasida » Piroplasmida » Babesiidae » Babesia » Babesia bovis
Distribution: sub-temperate and tropical regions
Life cycle: sporozoites directly infect erythrocytes
Chromosomes: 4
GC content: 44.32
Bases: 8.2 million
Genome: http://www.vetmed.wsu.edu/research_vmp/babesia-bovis/
http://www.sanger.ac.uk/Projects/B_bovis/
KEGG: bbo

References
Brayton KA, Lau AO, Herndon DR, Hannick L, Kappmeyer LS, Berens SJ, Bidwell SL, Brown WC, Crabtree J, Fadrosh D, Feldblum T, Forberger HA, Haas BJ, Howell JM, Khouri H, Koo H, Mann DJ, Norimine J, Paulsen IT, Radune D, Ren Q, Smith RK, Suarez CE, White O, Wortman JR, Knowles DP, McElwain TF, Nene VM. 2007. Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. PLoS pathogens 3:1401-13. (17953480)
de Vries E, Corton C, Harris B, Cornelissen AW, Berriman M. 2006. Expressed sequence tag (EST) analysis of the erythrocytic stages of Babesia bovis. Veterinary parasitology 138:61-74. (16530971)
Allred DR, Al-Khedery B. 2004. Antigenic variation and cytoadhesion in Babesia bovis and Plasmodium falciparum: different logics achieve the same goal. Molecular and biochemical parasitology 134:27-35. (14747140)
Al-Khedery B, Allred DR. 2006. Antigenic variation in Babesia bovis occurs through segmental gene conversion of the ves multigene family, within a bidirectional locus of active transcription. Molecular microbiology 59:402-14. (16390438)
Allred DR. 2003. Babesiosis: persistence in the face of adversity. Trends in parasitology 19:51-5. (12586467)
Barbour AG, Restrepo BI. . Antigenic variation in vector-borne pathogens. Emerging infectious diseases 6:449-57. (10998374)
Allred DR. 1998. Antigenic variation in Babesia bovis: how similar is it to that in Plasmodium falciparum? Annals of tropical medicine and parasitology 92:461-72. (9683897)
Dzikowski R, Deitsch K. 2006. Antigenic variation by protozoan parasites: insights from Babesia bovis. Molecular microbiology 59:364-6. (16390434)
Allred DR, Al-Khedery B. 2006. Antigenic variation as an exploitable weakness of babesial parasites. Veterinary parasitology 138:50-60. (16517078)

Last modified: 1? 14, 2013



Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan
System last updated Thu, January 24, 2013 14:25:29 JST / SVN revision: 1054
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